SMARTFlexDB

RNA conformational change on ligand binding

Multi-ligand pocket groups

Each card groups holo structures of a closely matched RNA bound by two or more different small molecules. Two RNA sequences are closely matched when they share an identical stretch of at least 12 consecutive nucleotides and at least 85% of the shorter sequence matches the longer one. The highlighted consensus residues show how far the binding sites overlap. Click a card for each ligand’s 2D structure and properties.