SMARTFlexDB

RNA conformational change on ligand binding

Matched RNA pockets bound to multiple ligands

Each card groups holo structures of a closely matched RNA (by sequence) bound by two or more different small molecules. The highlighted consensus residues indicate the extent to which the ligand-binding sites overlap. No apo structure is required — so a series may include structures excluded from the apo–holo database, such as cases in which the nominal apo structure contains a ligand in the corresponding pocket. Click a card to see every ligand's 2D structure and properties.